(S,R,S)-AHPC-PEG3-NH2 hydrochloride - CAS 2097971-11-2

(S,R,S)-AHPC-PEG3-NH2 hydrochloride is a crosslinker−E3 ligase ligand conjugate consisting of a von Hippel-Lindau (VHL)-recruiting ligand and a PEGylated crosslinker with terminal amine for reactivity with a carboxyl group on the target ligand. It has been used as a degrader building block in PROTAC for targeted protein degradation.

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Molecular Formula
C30H45N5O7S·xHCl
Molecular Weight
619.77 (free base)

(S,R,S)-AHPC-PEG3-NH2 hydrochloride

    • Specification
      • Shelf Life
        2 years
        Storage
        -20°C
        Synonyms
        VH 032-linker 1; (2S,4R)-1-((S)-14-Amino-2-(tert-butyl)-4-oxo-6,9,12-trioxa-3-azatetradecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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