(S,R,S)-AHPC-PEG2-azide - CAS 2010159-45-0

(S,R,S)-AHPC-PEG2-azide is a crosslinker−E3 ligase ligand conjugate consisting of a von Hippel-Lindau (VHL)-recruiting ligand and a PEGylated crosslinker with terminal azide for click chemistry with a target ligand. It has been used as a degrader building block in PROTAC for targeted protein degradation.

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Molecular Formula
C28H39N7O6S
Molecular Weight
601.72

(S,R,S)-AHPC-PEG2-azide

    • Specification
      • Shelf Life
        2 years
        Storage
        -20°C
        Synonyms
        (2S,4R)-1-((S)-2-(2-(2-(2-Azidoethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
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