Binding Affinity Measurement


* Please be kindly noted that our services and products can only be used for research to organizations or companies and not intended for any clinical or individuals.

Binding affinity measurement is an important test item related to proteolysis targeting chimera (PROTAC) technology. As a professional technical service company in the field of drug discovery and research, BOC Sciences provides outsourcing services for binding affinity testing. Our technical team has many years of experience in binding affinity measurement to ensure the accuracy and repeatability of the test.

Introduction

Binding affinity refers to the strength of interaction between a single biomolecule and its binding molecule / ligand, such as the strength of the interaction between the PROTAC ligand and the target protein or E3 ubiquitin ligase. The detection and analysis of the binding affinity help to further understand the PROTAC technology. In addition, PROTAC technology may also involve the interaction between other proteins and the interaction between drugs and proteins. Moreover, the detection of binding affinity is conducive to the identification and screening of PROTAC compounds or E3 ubiquitin ligases with stronger specificity. Therefore, in order to further optimize the PROTAC technology, it is often necessary to carry out binding affinity assay in the development of PROTAC technology.

Binding Affinity Measurement

Below is a list of our Binding Affinity Measurement Services (include but not limited to the following):

Our Technology Platforms for Binding Affinity Measurement Services (include but not limited to the following):

Our Advantages

Workflow of Binding Affinity Measurement Service

Binding Affinity Measurement

Reference:

  1. Gromiha, M.; et al. Protein–protein interactions: scoring schemes and binding affinity. Current Opinion in Structural Biology. 2017, 44: 31-38.

Online Inquiry


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USA

  • International: 1-631-504-6093
  • US & Canada (Toll free): 1-844-BOC(262)-0123
  • 45-16 Ramsey Road, Shirley, NY 11967, USA
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  • Fax: 1-631-614-7828

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