Live-Cell Assay


* Please be kindly noted that our services and products can only be used for research to organizations or companies and not intended for any clinical or individuals.

As a leading service provider in the field of drug discovery and research, BOC Sciences has established an advanced one-stop Proteolysis Targeting Chimeric (PROTAC) service platform to provide a number of related scientific research outsourcing services.

Introduction

In PROTAC technology, after delivering PROTAC compounds to living cells, it utilizes the ubiquitin proteasome system (UPS) to target the protein of interest (POI) and induce their degradation in living cells. Therefore, during the development or optimization processes of PROTAC technology, some relevant parameters, such as cell permeability and ligand-receptor binding, need to be analyzed and verified on the living cells platform. BOC Sciences provides high quality advanced live-cell assay platform to help customers further develop and optimize PROTAC technology. Our expert team has many years of experience in live-cell assays, which can guarantee to provide customers with high efficiency and high-quality services, helping customers get lower research costs and shorter research cycles.

Live-Cell Assay

Our Live-Cell Assay Services (include but are not limited to the following):

Our technology platform for Live-Cell Assay

As a professional company engaged in technology outsourcing services related to PROTAC technology, BOC Sciences has a set of advanced live-cell assays technology platforms, including surface plasmon resonance (SPR), SPR imaging for affinity-based biosensors, fluorescence resonance energy transfer (FRET), bioluminescence resonance energy transfer (BRET), etc.

Our Advantages

Workflow of Live-Cell Assay

Live-Cell Assay

References:

  1. Sun, X. Y.; et al. PROTACs: great opportunities for academia and industry. Signal Transduction and Targeted Therapy. 2019, 4: 64.
  2. Gu, S.; et al. Protacs: an emerging targeting technique for protein degradation in drug discovery. Bioessays. 2018, 40(4): e1700247.

Online Inquiry


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USA

  • International: 1-631-504-6093
  • US & Canada (Toll free): 1-844-BOC(262)-0123
  • 45-16 Ramsey Road, Shirley, NY 11967, USA
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  • Fax: 1-631-614-7828

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